RAD-140

Research showing that RAD-140 acts on selective androgen receptors exclusively in
muscle and bone tissues therefore it mimics hormone receptors that are very
similar to testosterone without the side effects because of its selective action.
Besides rapid increase in building muscular tissues research has shown RAD-140
shows strong increases in stamina and endurance during high intensity exercise
to go along with great increases in muscle recovery. Research studies have shown
that RAD-140 has greater anabolic effects than testosterone because it produces
more reinforced results without side effects and it’s great for those that need
supplemental hormonal therapy. RAD-140 had also shown to preserve neurons in the
brain and have neuroprotective properties as with testosterone and is a great
benefit to those with neurodegenerative diseases. Summing everything up RAD-140
is a great SARM for rapid increases in muscle growth, improvements in endurance,
and increases overall athletic performance.

2-Chloro-4-({1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-
hydroxypropyl}amino)-3-methylbenzonitril

Testolone (RAD140) is a selective androgen receptor modulator (SARM) that is still under development by Radius Health Inc.

What are sarms?

SARMS are in the class of androgen receptor ligands that bind to androgen receptors.  They started being researched in the 1940’s via the modification of the testosterone molecule. Generally, they were developed to help decrease obesity, improve bone health, improve disease fighting, and to prevent muscle wasting. Since RAD140 belongs to the class of SARMS, it has similar effects to those of anabolic steroids, but without the harsh side effects because it acts on the androgen receptors in a selective manner.

RAD140 is one of the newest SARMS, and its objective is to give a blast of testosterone without the negative side effects associated to steroid use. Hence the reason why it is an alternative to testosterone replacement therapy. Specifically, it has been shown to interact with hormonal receptors in the tissues in the same way as a large doses of testosterone do. Furthermore, it also exhibited a greater anabolic effect than testosterone, and a more reinforced effect as well.

There are several groups of individuals who can benefit from Testolone (RAD140) use.

  1. Those who have low testosteronebecause of health issues, or prior abuse of anabolic steroids.

2. Bodybuilders who want to bridge between steroid cycles. Imagine being able to use testosterone in between your existinganabolic steroid cycles without worrying about suppression and damaging your HPTA. This will allow you to keep more strength and muscle off cycle then you ever have before.

3. Those who want to use a performance enhancing drug, but are concerned with the possible side effects. In such situation, one could cycle RAD140 instead of anabolic steroids and not worry about shutdown or the negative health effects caused by steroids.

4. Those sensitive to gynecomastia. RAD140 is like using testosterone, but without the risk of estrogenic side effects because it does not aromatize into estrogen. Therefore, if a testosterone base is needed during a cycle, RAD140 can be used without fear of getting bitch tits or bloating.

Due to the fact that Testolone (RAD140) is so new and is still in Phase 1 of trials, studies on this SARM are few. However, so far it has been shown to increase endurance, stamina, and speed during an athlete’s training. Obviously, it is capable of increasing strength and muscle volume in a much shorter time, especially in those who are deficient in the male hormone testosterone. Moreover, RAD140 has anti-catabolic properties, so it will be a great help at preventing muscle wasting problems.

Up to the date, RAD140 did not show any side effects in studies. This means that there is no need to be concerned about estrogen, progesterone, or prolactin related side effects. Additionally, suppression has been shown to be minimal compared to testosterone. However, keep in mind that this is a very new drug, and it is wise to keep an eye on user results over the next year or two.

RAD140 can be dosed at 20-30 milligrams (mg) per day, and thanks to a relatively long half life, you can get away with only once a day dosing schedule. Regarding the possible cycle durations, RAD140’s length of use can vary from 6 to 12 weeks. Since it usually comes in liquid form, this SARM is squirted into the mouth, swallowed, and chased down with juice. There is no need to let it sit in the mouth or under tongue; in fact, sublingual use is highly discouraged.